Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT0BE68)

DTT Name	Membrane glycoprotein OX2 (CD200)
Synonyms	OX2 membrane glycoprotein; OX-2 membrane glycoprotein; My033; MOX2; MOX1
Gene Name	CD200
DTT Type	Clinical trial target	[1]
BioChemical Class	Immunoglobulin
UniProt ID	OX2G_HUMAN
TTD ID	T81695
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MERLVIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEAL IVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYM CLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIE NSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLL LSIVSLVILLVLISILLYWKRHRNQDRGELSQGVQKMT
Function	May regulate myeloid cell activity in a variety of tissues. Costimulates T-cell proliferation.
Reactome Pathway	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (R-HSA-198933 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ALXN6000	DMH5LFR	Acute myeloid leukaemia	2A60	Phase 2	[1]
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References

1	American Society of Hematology, 52nd Annual Meeting and Exposition. P T. 2011 February; 36(2): 100-103.