Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT0RGE9)

• DTT Name: Lysine-specific demethylase 4 (KDM4)
• Synonyms: KDM4
• Gene Name: KDM4
• DTT Type: Patented-recorded target; [1]
• UniProt ID: NOUNIPROTAC
• TTD ID: T10565

Molecular Interaction Atlas (MIA) of This DTT

20 Patented Agent(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2,2-bipyridyl derivative 1	DMRTDOA	N. A.	N. A.	Patented	[1]
2,2-bipyridyl derivative 2	DMYLQZ1	N. A.	N. A.	Patented	[1]
2,2-bipyridyl derivative 3	DMPQF78	N. A.	N. A.	Patented	[1]
2,2-bipyridyl derivative 4	DMTYPBM	N. A.	N. A.	Patented	[1]
2,2-bipyridyl derivative 5	DMEJOPL	N. A.	N. A.	Patented	[1]
Hydroxamate analog 2	DMBMG1S	N. A.	N. A.	Patented	[1]
Hydroxamate analog 3	DMDQYJ1	N. A.	N. A.	Patented	[1]
N-oxalylglycine derivative 1	DMUHFLQ	N. A.	N. A.	Patented	[1]
N-oxalylglycine derivative 2	DMDJC96	N. A.	N. A.	Patented	[1]
N-oxalylglycine derivative 3	DMQF0RY	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-48	DMBPT9Z	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-49	DM2HG9U	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-50	DMIVJ2W	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-51	DMNPC0H	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-52	DMAH1G7	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-53	DMONWYI	N. A.	N. A.	Patented	[1]
PMID25468267-Compound-54	DMI93AX	N. A.	N. A.	Patented	[1]
Pyridine-2,4-dicarboxylic acid derivative 1	DMZSTCQ	N. A.	N. A.	Patented	[1]
Pyridine-2,4-dicarboxylic acid derivative 2	DMGCMF5	N. A.	N. A.	Patented	[1]
Pyridine-2,4-dicarboxylic acid derivative 3	DMCUP4L	N. A.	N. A.	Patented	[1]

References

• [1] KDM4 histone demethylase inhibitors for anti-cancer agents: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):135-44.