Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT2GVH5)

DTT Name Isomerase unspecific (IsoM)
Gene Name IsoM
DTT Type
Discontinued target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T21324

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
2 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isbogrel DM1B8NU Angina pectoris BA40 Discontinued in Preregistration [1]
Nafagrel DMKF3TD Asthma CA23 Discontinued in Phase 2 [2]
------------------------------------------------------------------------------------

References

1 Beneficial effect of CV-4151 (Isbogrel), a thromboxane A2 synthase inhibitor, in a rat middle cerebral artery thrombosis model. Thromb Res. 1995 Jul 1;79(1):95-107.
2 FMLP actions and its binding sites in isolated human coronary arteries. J Mol Cell Cardiol. 1997 Mar;29(3):881-94.