Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT3PTB6)

DTT Name Translationally-controlled tumor protein (TPT1)
Synonyms p23; TPT1; TCTP; Histamine-releasing factor; HRF; Fortilin
Gene Name TPT1
DTT Type
Discontinued target
 [1]
UniProt ID
TCTP_HUMAN
TTD ID
T77473
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGE
GTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAE
QIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC
Function Involved in calcium binding and microtubule stabilization.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
CER-227185 DMMZ79C Acute myeloid leukaemia 2A60 Discontinued in Phase 1/2 [1]
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Molecular Expression Atlas (MEA) of This DTT

Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This DTT
Disease Name ICD 11 Studied Tissue p-value Fold-Change Z-score
Acute myelocytic leukaemia 2C82 Bone marrow 1.08E-17 0.1 1.22
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References

1 Clinical pipeline report, company report or official report of Cerep.