General Information of Drug Therapeutic Target (DTT) (ID: TT5D314)

DTT Name Lipophilin-B (SCGB1D2)
Synonyms Secretoglobin family 1D member 2; SCGB1D2
Gene Name SCGB1D2
DTT Type
Literature-reported target
[1]
BioChemical Class
Secretoglobin family
UniProt ID
SG1D2_HUMAN
TTD ID
T46824
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MKLSVCLLLVTLALCCYQANAEFCPALVSELLDFFFISEPLFKLSLAKFDAPPEAVAAKL
GVKRCTDQMSLQKRSLIAEVLVKILKKCSV
Function May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.

References

1 Serum antibodies to lipophilin B detected in late stage breast cancer patients. Clin Cancer Res. 2003 Feb;9(2):749-54.