Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT5GKHN)

DTT Name	Lymphocyte antigen 6K (LY6K)
Synonyms	Ly-6K; CO16
Gene Name	LY6K
DTT Type	Literature-reported target	[1]
UniProt ID	LY6K_HUMAN
TTD ID	T57843
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MALLALLLVVALPRVWTDANLTARQRDPEDSQRTDEGDNRVWCHVCERENTFECQNPRRC KWTEPYCVIAAVKIFPRFFMVAKQCSAGCAAMERPKPEEKRFLLEEPMPFFYLKCCKIRY CNLEGPPINSSVFKEYAGSMGESCGGLWLAILLLLASIAAGLSLS
Function	Required for sperm migration into the oviduct and male fertility by controlling binding of sperm to zona pellucida (By similarity). May play a role in cell growth.
Reactome Pathway	Post-translational modification (R-HSA-163125 )

References

1	Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcin... Int J Cancer. 2003 Mar 1;103(6):768-74.