Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT64REZ)

• DTT Name: Neuropeptide Y (NPY)
• Synonyms: Pro-neuropeptide Y
• Gene Name: NPY
• DTT Type: Literature-reported target; [1]
• UniProt ID: NPY_HUMAN
• TTD ID: T51671
• Sequence:
  MLGNKRLGLSGLTLALSLLVCLGALAEAYPSKPDNPGEDAPAEDMARYYSALRHYINLIT
  RQRYGKRSSPETLISDLLMRESTENVPRTRLEDPAMW
• Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
• KEGG Pathway:
  cAMP signaling pathway (hsa04024)
  Adipocytokine signaling pathway (hsa04920)
  Alcoholism (hsa05034)
• Reactome Pathway:
  G alpha (i) signalling events (R-HSA-418594)
  Peptide ligand-binding receptors (R-HSA-375276)

Molecular Interaction Atlas (MIA) of This DTT

2 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alpha-Aminoisobutyric Acid	DM9GXFJ	Discovery agent	N.A.	Investigative	[1]
L-Tyrosinamide	DMGVELK	Discovery agent	N.A.	Investigative	[1]

References

• [1] The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.