General Information of Drug Therapeutic Target (DTT) (ID: TT6NHYC)

DTT Name Pneumocystis carinii Dihydropteroate synthase (PC DHPS)
Synonyms PC DHPS
Gene Name PC DHPS
DTT Type
Successful target
[1]
UniProt ID
FOL1_PNECA
TTD ID
T16761
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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EC Number
EC 2.5.1.15
Sequence
SFRSYKAPTYIMAILNLTPDSFFDGGIHSYDSVLIDVEKFINAGATIIDIGGQSTRPGSY
IIPLEEEIFRVIPAIKYLQKTYPDILISIDTFRSEVAEQAVKAGASLVNDISGGRYDPKM
FNTVARLKVPICIMHMRGNFLNMDNLTDYGTDIIEQITIELEKLLNSAEKSGIPRWNIIL
DPGLGFSKTLHQNIELLRRFNELKSKNCFNGLPWLLGPSRKRFTGFITGDNMPKDRIWGT
VAAVVASISGGCDIIRVHDVYEMYKISKMSDAIWKEIY
Function Catalyzes three sequential steps of tetrahydrofolate biosynthesis.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Approved Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dapsone DM4LT8A Acne vulgaris ED80 Approved [1]
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References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.