Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TT8E7Z0)

DTT Name Free radical (FRD)
Gene Name FRD
DTT Type
Clinical trial target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T99566

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
3 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disufenton sodium DMJS8V3 Ischemia 8B10-8B11 Phase 3 [1]
RRx-001 DMQM2FH Small-cell lung cancer 2C25.Y Phase 3 [2]
SM-88 DMD9ISG Pancreatic cancer 2C10 Phase 2/3 [3]
------------------------------------------------------------------------------------

References

1 NXY-059, a free radical--trapping agent, substantially lessens the functional disability resulting from cerebral ischemia in a primate species. Stroke. 2001 Jan;32(1):190-8.
2 Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials. Cancer Res. 2012 May 15;72(10):2600-8.
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)