Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTCDFR1)
DTT Name | S100 calcium-binding protein A3 (S100A3) | ||||
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Synonyms | S100E; Protein S-100E | ||||
Gene Name | S100A3 | ||||
DTT Type |
Literature-reported target
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[1] | |||
BioChemical Class |
S100 calcium-binding protein
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UniProt ID | |||||
TTD ID | |||||
3D Structure | |||||
Sequence |
MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMS
VLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ |
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Function | Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation. | ||||