Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTCY4SB)

DTT Name Aurora kinase (AURK)
Synonyms Serine/threonine kinase
Gene Name NO-GeName
DTT Type
Clinical trial target
 [1]
Related Disease
Lung cancer [ICD-11: 2C25]
UniProt ID
NOUNIPROTAC
TTD ID
T01011

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
AZD2811 DMYUNXP Small-cell lung cancer 2C25.Y Phase 2 [2]
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1 Patented Agent(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diamidothiazole derivative 1 DM02V5Q N. A. N. A. Patented [1]
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References

1 Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70.
2 Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo. Sci Transl Med. 2016 Feb 10;8(325):325ra17.