General Information of Drug Therapeutic Target (DTT) (ID: TTDS503)

DTT Name Beta-crystallin B1 (CRYBB1)
Synonyms CRYBB1; Beta B1-crystallin
Gene Name CRYBB1
DTT Type
Literature-reported target
[1]
UniProt ID
CRBB1_HUMAN
TTD ID
T38622
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSQAAKASASATVAVNPGPDTKGKGAPPAGTSPSPGTTLAPTTVPITSAKAAELPPGNYR
LVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKGE
YPRWNTWSSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFS
DRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLE
GSFPVLATEPPK
Function Crystallins are the dominant structural components of the vertebrate eye lens.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Double Oxidized Cysteine DM6TU84 Discovery agent N.A. Investigative [1]
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References

1 How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.