Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTFPSHI)

• DTT Name: Wnt signaling pathway (Wnt pathway)
• Gene Name: Wnt pathway
• DTT Type: Clinical trial target; [1]
• UniProt ID: NOUNIPROTAC
• TTD ID: T54379

Molecular Interaction Atlas (MIA) of This DTT

5 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SM04554	DM30JWZ	Alopecia	ED70	Phase 2/3	[2]
SM-04690	DMOLTAD	Osteoarthritis	FA00-FA05	Phase 2	[3]
CWP232291	DMBUYIK	Acute myeloid leukaemia	2A60	Phase 1/2	[1]
SM04755	DM491NI	Liver cancer	2C12	Phase 1	[4]
SM08502	DM4KLNA	Solid tumour/cancer	2A00-2F9Z	Phase 1	[1]

References

• [1] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] Clinical pipeline report, company report or official report of Phrma.org Arthritis 2014.
• [4] A Phase 1, Open-Label, Dose-Escalation, Dose-Finding Study Evaluating the Safety and Pharmacokinetics of SM04755 in Subjects with Advanced Colorectal, Gastric, Hepatic, or Pancreatic Cancer.