Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTGD6BY)

DTT Name	TNF-alpha/IL-1 beta production (TNFA/IL1B produ)
Gene Name	TNFA/IL1B produ
DTT Type	Clinical trial target	[1]
UniProt ID	NOUNIPROTAC
TTD ID	T72182

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Esonarimod	DM4YGWA	Arthritis	FA20	Phase 3	[1]
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References

1	KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line. Drugs Exp Clin Res. 2002;28(5):197-205.