Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTGQA9W)

DTT Name	Apolipoprotein A-II (APOA2)
Synonyms	Apolipoprotein A2; ApoA-II; Apo-AII
Gene Name	APOA2
DTT Type	Literature-reported target	[1]
BioChemical Class	Apolipoprotein
UniProt ID	APOA2_HUMAN
TTD ID	T75655
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MKLLAATVLLLTICSLEGALVRRQAKEPCVESLVSQYFQTVTDYGKDLMEKVKSPELQAE AKSYFEKSKEQLTPLIKKAGTELVNFLSYFVELGTQPATQ
Function	May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
KEGG Pathway	PPAR signaling pathway (hsa03320 )
Reactome Pathway	PPARA activates gene expression (R-HSA-1989781 ) Retinoid metabolism and transport (R-HSA-975634 ) Chylomicron-mediated lipid transport (R-HSA-174800 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
B-Octylglucoside	DMMO75G	Discovery agent	N.A.	Investigative	[1]
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References

1	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.