Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTHSVK0)

DTT Name Thioredoxin-like protein 2b (NME9)
Synonyms Txl-2; Thioredoxin-like protein 2; Thioredoxin domain-containing protein 6; NME9
Gene Name NME9
DTT Type
Literature-reported target
 [1]
UniProt ID
TXND6_HUMAN
TTD ID
T29363
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGSRKKEIALQVNISTQELWEEMLSSKGLTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDL
LHFALAEADRLDVLEKYRGKCEPTFLFYAGGELVAVVRGANAPLLQKTILDQLEAEKKVL
AEGRERKVIKDEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIM
KIQEAGFEILTNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFED
VVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKF
SDKDTEAPQGGEAEATAGPTEALCFPEDVD
Function May be a regulator of microtubule physiology.

References

1 Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-B pathway. Cancer Lett. 2015 Jul 28;363(2):119-26.