General Information of Drug Therapeutic Target (DTT) (ID: TTHYMUV)

DTT Name Intestinal alkaline phosphatase
Synonyms Intestinal-type alkaline phosphatase; ALPI
Gene Name ALPI
BioChemical Class
Single Protein
UniProt ID
PPBI_HUMAN
TTD ID
TE0068
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
Function Extracellular region, plasma membrane, alkaline phosphatase activity, magnesium ion binding, protease binding, zinc ion binding, dephosphorylation, digestion, phosphatidic acid biosynthetic process