General Information of Drug Therapeutic Target (DTT) (ID: TTI7ENL)

DTT Name Skeletal muscle LIM-protein 1 (FHL1)
Synonyms Skeletal muscle LIMprotein 1; SLIM1; SLIM; Four and a half LIM domains protein 1; FHL1
Gene Name FHL1
DTT Type
Literature-reported target
[1]
UniProt ID
FHL1_HUMAN
TTD ID
T81135
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF
WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT
VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP
WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHP
VSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVK
APVWWPMKDNPGTTTASTAKNAP
Function May have an involvement in muscle development or hypertrophy.
KEGG Pathway
JAK-STAT signaling pathway (hsa04630 )

References

1 Epigenetic analysis of FHL1 tumor suppressor gene in human liver cancer. Oncol Lett. 2017 Nov;14(5):6109-6116.