Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTJD1TI)

DTT Name	Zinc finger protein OZF (ZNF146)
Synonyms	Zinc finger protein 146; Only zinc finger protein; OZF
Gene Name	ZNF146
DTT Type	Literature-reported target	[1]
BioChemical Class	Zinc-finger
UniProt ID	OZF_HUMAN
TTD ID	T86587
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MSHLSQQRIYSGENPFACKVCGKVFSHKSNLTEHEHFHTREKPFECNECGKAFSQKQYVI KHQNTHTGEKLFECNECGKSFSQKENLLTHQKIHTGEKPFECKDCGKAFIQKSNLIRHQR THTGEKPFVCKECGKTFSGKSNLTEHEKIHIGEKPFKCSECGTAFGQKKYLIKHQNIHTG EKPYECNECGKAFSQRTSLIVHVRIHSGDKPYECNVCGKAFSQSSSLTVHVRSHTGEKPY GCNECGKAFSQFSTLALHLRIHTGKKPYQCSECGKAFSQKSHHIRHQKIHTH
Function	A nuclear zinc finger protein consisting of a single domain of 10 zinc finger motifs of the Kruppel type, preceded by 10 amino acids. Involved in gene regulation and tumorigenesis.

References

1	The zinc finger protein OZF (ZNF146) is overexpressed in colorectal cancer. J Pathol. 2003 Jun;200(2):177-82.