General Information of Drug Therapeutic Target (DTT) (ID: TTKJX1V)

DTT Name Fibroblast growth factor-14 (FGF14)
Synonyms Fibroblast growth factor homologous factor 4; Fibroblast growth factor 14; FHF4; FGF14
Gene Name FGF14
DTT Type
Literature-reported target
[1]
BioChemical Class
Growth factor
UniProt ID
FGF14_HUMAN
TTD ID
T29481
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLCNGNLVDIFSKVRIFGLKKRR
LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK
TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ
AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP
VNKSKTT
Function Probably involved in nervous system development and function.
KEGG Pathway
Spinocerebellar ataxia (hsa05017 )
Reactome Pathway
Phase 0 - rapid depolarisation (R-HSA-5576892 )

References

1 Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. Mol Neurobiol. 2016 Dec;53(10):7254-7270.