Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTLH8WG)

DTT Name	HSP27 messenger RNA (HSPB3 mRNA)
Synonyms	Protein 3 (mRNA); HspB3 (mRNA); Heat shock protein beta-3 (mRNA); Heat shock 17 kDa protein (mRNA); HSPL27 (mRNA); HSP 17 (mRNA)
Gene Name	HSPB3
DTT Type	Literature-reported target	[1]
BioChemical Class	mRNA target
UniProt ID	HSPB3_HUMAN
TTD ID	T12486
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MAKIILRHLIEIPVRYQEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAA ETPPREGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKL PDGVEIKDLSAVLCHDGILVVEVKDPVGTK
Function	Inhibitor of actin polymerization.

References

1	Heat Shock Protein 27, a Novel Regulator of Transforming Growth Factor Induced Resistance to Cisplatin in A549 Cell. Pharmacology. 2017;100(5-6):283-291.