General Information of Drug Therapeutic Target (DTT) (ID: TTMRE4Q)

DTT Name Homeobox protein Hox-A7 (HOXA7)
Synonyms HoxA7; Hox-1A; Hox 1.1; Homeobox protein Hox-1A; Homeobox protein Hox 1.1; HOX1A
Gene Name HOXA7
DTT Type
Literature-reported target
[1]
BioChemical Class
Antp homeobox
UniProt ID
HXA7_HUMAN
TTD ID
T26338
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSP
LYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIY
PWMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQN
RRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEEDDDEEEEDEEE
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

References

1 Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein. Oncogene. 2004 Apr 22;23(19):3385-94.