Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTMT6VE)

DTT Name	Tetraspanin-7 (TSPAN7)
Synonyms	TSPAN7; TALLA-1; T-cell acute lymphoblastic leukemia-associated antigen 1; T-cell acute lymphoblastic leukemia associated antigen 1; Membrane component, X chromosome, surface marker 1; Cell surface glycoprotein A15; CD231 antigen
Gene Name	TSPAN7
DTT Type	Literature-reported target	[1]
BioChemical Class	Tetraspanin family
UniProt ID	TSN7_HUMAN
TTD ID	T65161
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MASRRMETKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPY VLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTF LRTYTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLEHGIPPSCCMNETD CNPQDLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLACCLSRF ITANQYEMV
Function	May be involved in cell proliferation and cell motility.
KEGG Pathway	Transcriptional misregulation in cancer (hsa05202 )
Reactome Pathway	Trafficking of GluR2-containing AMPA receptors (R-HSA-416993 ) Cell surface interactions at the vascular wall (R-HSA-202733 )

References

1	A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion pro... Am J Pathol. 2003 Dec;163(6):2165-72.