Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTMVAIU)

DTT Name	Thymosin beta-4 (TMSB4X)
Synonyms	TMSB4X; T beta-4; Fx
Gene Name	TMSB4X
DTT Type	Literature-reported target	[1]
BioChemical Class	Thymosin family
UniProt ID	TYB4_HUMAN
TTD ID	T85005
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MSDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Function	Seraspenide inhibits the entry of hematopoietic pluripotent stem cellsinto the S-phase.
KEGG Pathway	Regulation of actin cytoskeleton (hsa04810 )
Reactome Pathway	Platelet degranulation (R-HSA-114608 )

References

1	Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling. Sci Rep. 2017 Jun 19;7(1):3815.