Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTNSXG2)

DTT Name Human immunodeficiency virus TAR RNA (HIV TAR-RNA)
Gene Name HIV TAR-RNA
DTT Type
Literature-reported target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T76563

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
3 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
2,4-diaminoquinozalines and quinoxaline-2,3-diones DMS1YXL Discovery agent N.A. Investigative [1]
Chimeric small nucleolar RNA-TAR decoy DMJATBL Discovery agent N.A. Investigative [2]
Diazaborines DM5UFZX Discovery agent N.A. Investigative [3]
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References

1 RNA as a target for small molecules. Curr Opin Chem Biol. 2000 Dec;4(6):678-86.
2 A nucleolar TAR decoy inhibitor of HIV-1 replication. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14047-52.
3 Neomycin B-arginine conjugate, a novel HIV-1 Tat antagonist: synthesis and anti-HIV activities. Biochemistry. 2001 Dec 25;40(51):15612-23.