General Information of Drug Therapeutic Target (DTT) (ID: TTNWOIT)

DTT Name Prostate-associated gene 5 protein (PAGE5)
Synonyms PAGE-5; P antigen family member 5; GAGEE1; G antigen family E member 1; Cancer/testis antigen 16.1; CT16.1
Gene Name PAGE5
DTT Type
Literature-reported target
[1]
UniProt ID
PAGE5_HUMAN
TTD ID
T52719
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQAPWAGNRGWAGTREEVRDMSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEE
PPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPT
KVLEAGEGQL
Function
A member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues. The encoded protein may protect cells from programmed cell death. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found.

References

1 Melanoma-associated cancer-testis antigen 16 (CT16) regulates the expression of apoptotic and antiapoptotic genes and promotes cell survival. PLoS One. 2012;7(9):e45382.