Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTO1ENI)
| DTT Name | HUMAN FK506 binding protein 7 (FKBP7) | ||||
|---|---|---|---|---|---|
| Synonyms | Rotamase; PPIase FKBP7; Peptidyl-prolyl cis-trans isomerase FKBP7; FKBP-7; FKBP-23; FK506-binding protein 7; 23 kDa FKBP; 23 kDa FK506-binding protein | ||||
| Gene Name | FKBP7 | ||||
| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| EC Number |
EC 5.2.1.8
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| Sequence |
MPKTMHFLFRFIVFFYLWGLFTAQRQKKEESTEEVKIEVLHRPENCSKTSKKGDLLNAHY
DGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCPGEKRKVVIPPSFAYG KEGYAEGKIPPDATLIFEIELYAVTKGPRSIETFKQIDMDNDRQLSKAEINLYLQREFEK DEKPRDKSYQDAVLEDIFKKNDHDGDGFISPKEYNVYQHDEL |
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| Function | Human protein FK506 binding protein 7 interacts with SARS-CoV-2 Orf8 protein with high significance, which indicates FKBP7 as a potential therapeutic target. | ||||