Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTO7FVG)

DTT Name Heat shock protein 90 (HSP90)
Gene Name HSP90
DTT Type
Clinical trial target
 [1]
BioChemical Class
Heat shock protein
UniProt ID
NOUNIPROTAC
TTD ID
T03963

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
4 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
RNS-60 DMDNRU1 Asthma CA23 Phase 2 [1]
ADX-1612 DM86WI0 Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1 [2]
LAM-003 DMQHWMJ Acute myeloid leukaemia 2A60 Phase 1 [3]
RTA 901 DMA6JME Diabetic neuropathy 8C0Z Phase 1 [4]
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References

1 Clinical pipeline report, company report or official report of Revalesio.
2 Role of Ganetespib, an HSP90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice. Int J Mol Sci. 2023 Mar 6;24(5):5014.
3 LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML. Blood Adv. 2019 Nov 26;3(22):3661-3673.
4 Clinical pipeline report, company report or official report of Reata Pharmaceuticals.