Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTONPVW)

DTT Name	Uteroglobin (SCGB1A1)
Synonyms	Urine protein 1; Urinary protein 1; UP-1; Secretoglobin family 1A member 1; SCGB1A1; Clara cells 10 kDa secretory protein; Clara cell phospholipid-binding protein; CCPBP; CC10
Gene Name	SCGB1A1
DTT Type	Literature-reported target	[1]
BioChemical Class	Secretoglobin family
UniProt ID	UTER_HUMAN
TTD ID	T93484
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGA QLKKLVDTLPQKPRESIIKLMEKIAQSSLCN
Function	Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

References

1	Prognostic significance of low serum levels of Clara cell phospholipid-binding protein in occupational aluminium neurotoxicity. J Inorg Biochem. 2005 Sep;99(9):1904-11.