Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTPL1TK)
| DTT Name | Lysophosphatidic acid transferase (AGPAT1) | ||||
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| Synonyms | Protein G15; AGPAT1; 1acylsnglycerol3phosphate acyltransferase alpha; 1acylglycerol3phosphate Oacyltransferase 1; 1AGPAT 1; 1AGP acyltransferase 1 | ||||
| Gene Name | AGPAT1 | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| BioChemical Class |
Acyltransferase
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| EC Number |
EC 2.3.1.51
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| Sequence |
MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRG
RNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGR CVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGT RNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVPTE GLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG |
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| Function | Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. | ||||
| KEGG Pathway | |||||
| Reactome Pathway | |||||
| BioCyc Pathway | |||||