General Information of Drug Therapeutic Target (DTT) (ID: TTPR5SX)

DTT Name S100 calcium-binding protein A4 (S100A4)
Synonyms Protein S100-A4; Protein Mts1; Placental calcium-binding protein; Metastasin; MTS1; Calvasculin; CAPL
Gene Name S100A4
DTT Type
Literature-reported target
[1]
BioChemical Class
S100 calcium-binding protein
UniProt ID
S10A4_HUMAN
TTD ID
T35265
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MACPLEKALDVMVSTFHKYSGKEGDKFKLNKSELKELLTRELPSFLGKRTDEAAFQKLMS
NLDSNRDNEVDFQEYCVFLSCIAMMCNEFFEGFPDKQPRKK
Function
collagen-containing extracellular matrix, extracellular exosome, extracellular region, extracellular space, nucleus, perinuclear region of cytoplasm, calcium ion binding, identical protein binding, RAGE receptor binding, RNA binding

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Preclinical Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
SP-MET-1 DMO2UKI Breast cancer 2C60-2C65 Preclinical [1]
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References

1 Lost in migration. Nat Biotechnol. 2010 Mar;28(3):214-29.