General Information of Drug Therapeutic Target (DTT) (ID: TTREV7X)

DTT Name Virus Cysteine proteinase (Viru VCATH)
Synonyms Viral cathepsin; VCATH; V-cath; CP of Cydia pomonella granulosis virus
Gene Name Viru VCATH
DTT Type
Literature-reported target
[1]
BioChemical Class
Peptidase
UniProt ID
CATV_GVCPM
TTD ID
T30292
EC Number
EC 3.4.22.50
Sequence
MTKLLNFVILASVLTVTAHALTYDLNNSDELFKNFAIKYNKTYVSDEERAIKLENFKNNL
KMINEKNMASKYAVFDINEYSDLNKNALLRRTTGFRLGLKKNPSAFTMTECSVVVIKDEP
QALLPETLDWRDKHGVTPVKNQMECGSCWAFSTIANIESLYNIKYDKALNLSEQHLVNCD
NINNGCAGGLMHWALESILQEGGVVSAENEPYYGFDGVCKKSPFELSISGSRRYVLQNEN
KLRELLVVNGPISVAIDVSDLINYKAGIADICENNEGLNHAVLLVGYGVKNDVPYWILKN
SWGAEWGEEGYFRVQRDKNSCGMMNEYASSAIL
Function
Cysteine protease that plays an essential role in host liquefactionto facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
E-64 DMMOPAK Discovery agent N.A. Investigative [1]
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References

1 Characterization of a cysteine proteinase from Taenia crassiceps cysts. Mol Biochem Parasitol. 1997 Apr;85(2):243-53.