Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTS05MJ)

DTT Name Neuritin (NRN1)
Synonyms NRN
Gene Name NRN1
DTT Type
Literature-reported target
 [1]
UniProt ID
NRN1_HUMAN
TTD ID
T55465
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGLKLNGRYISLILAVQIAYLVQAVRAAGKCDAVFKGFSDCLLKLGDSMANYPQGLDDKT
NIKTVCTYWEDFHSCTVTALTDCQEGAKDMWDKLRKESKNLNIQGSLFELCGSGNGAAGS
LLPAFPVLLVSLSAALATWLSF
Function Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Reactome Pathway
Post-translational modification (R-HSA-163125 )

References

1 Overexpression of neuritin in gastric cancer. Oncol Lett. 2015 Dec;10(6):3832-3836.