Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTSM9YR)
| DTT Name | Folate receptor gamma (FOLR3) | ||||
|---|---|---|---|---|---|
| Synonyms | Folate receptor 3; FRgamma; FOLR3 | ||||
| Gene Name | FOLR3 | ||||
| DTT Type |
Literature-reported target
|
[1] | |||
| BioChemical Class |
Folate receptor
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| Sequence |
MDMAWQMMQLLLLALVTAAGSAQPRSARARTDLLNVCMNAKHHKTQPSPEDELYGQCSPW
KKNACCTASTSQELHKDTSRLYNFNWDHCGKMEPTCKRHFIQDSCLYECSPNLGPWIRQV NQSWRKERILNVPLCKEDCERWWEDCRTSYTCKSNWHKGWNWTSGINECPAGALCSTFES YFPTPAALCEGLWSHSFKVSNYSRGSGRCIQMWFDSAQGNPNEEVAKFYAAAMNAGAPSR GIIDS |
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| Function | Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate. | ||||
| KEGG Pathway | |||||
| Reactome Pathway | |||||