Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTSVQWU)

DTT Name	Leishmania major Proteasome (Leishm Proteasome)
Gene Name	Leishm Proteasome
DTT Type	Clinical trial target	[1]
UniProt ID	Q4QH56_LEIMA ; Q4Q1Q9_LEIMA
TTD ID	T07816
KEGG Pathway	Proteasome (lma03050 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
LXE408	DMLBD5I	Visceral leishmaniasis	1F54.0	Phase 2	[1]
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References

1	Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases. J Med Chem. 2020 Oct 8;63(19):10773-10781.