Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTT9MRQ)

DTT Name Cell surface protein HB15 (CD83)
Synonyms hCD83; CD83 antigen; Bcell activation protein; B-cell activation protein
Gene Name CD83
DTT Type
Literature-reported target
 [1]
BioChemical Class
Immunoglobulin
UniProt ID
CD83_HUMAN
TTD ID
T90800
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MSRGLQLLLLSCAYSLAPATPEVKVACSEDVDLPCTAPWDPQVPYTVSWVKLLEGGEERM
ETPQEDHLRGQHYHQKGQNGSFDAPNERPYSLKIRNTTSCNSGTYRCTLQDPDGQRNLSG
KVILRVTGCPAQRKEETFKKYRAEIVLLLALVIFYLTLIIFTCKFARLQSIFPDFSKAGM
ERAFLPVTSPNKHLGLVTPHKTELV
Function May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

References

1 CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma. Haematologica. 2018 Apr;103(4):655-665.