Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTTG60L)

DTT Name	CAP-dependent endonuclease (CDE)
Gene Name	CDE
DTT Type	Discontinued target	[1]
UniProt ID	NOUNIPROTAC
TTD ID	T52969

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Discontinued Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GSK184072	DMMIR1K	Colon cancer	2B90.Z	Discontinued in Phase 2	[1]
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1 Investigative Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
4-substituted 2,4-dioxobutanoic acids	DMELGKY	Discovery agent	N.A.	Investigative	[2]
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References

1	Synthesis of natural flutimide and analogous fully substituted pyrazine-2,6-diones, endonuclease inhibitors of influenza virus. J Org Chem. 2001 Aug 10;66(16):5504-16.
2	Anti-influenza virus activities of 4-substituted 2,4-dioxobutanoic acid inhibitors. Antimicrob Agents Chemother. 1996 May;40(5):1304-7.