Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTUH273)

DTT Name	Choriogonadotropin beta (CG-beta)
Synonyms	Chorionic gonadotropin beta subunit; Chorionic gonadotrophin beta subunit; CG-beta
Gene Name	CGB3
DTT Type	Clinical trial target	[1]
BioChemical Class	Hormone
UniProt ID	CGB3_HUMAN
TTD ID	T06575
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MEMFQGLLLLLLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPT MTRVLQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC GGPKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ
Function	Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
Reactome Pathway	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors (R-HSA-8866910 ) Glycoprotein hormones (R-HSA-209822 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
CDX-1307	DM8UQJG	Bladder cancer	2C94	Phase 2	[1]
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References

1	CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer. Expert Rev Vaccines. 2011 Jun;10(6):733-42.