Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTV2DON)

DTT Name Cellular retinol binding protein III (RBP5)
Synonyms Retinol-binding protein 5; RBP5; HRBPiso; CRBP-III
Gene Name RBP5
DTT Type
Literature-reported target
 [1]
BioChemical Class
Calycin family
UniProt ID
RET5_HUMAN
TTD ID
T38093
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRN
YTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLEL
TARDAVCEQVFRKVR
Function Intracellular transport of retinol.

References

1 Cellular retinol-binding protein type III is a PPARgamma target gene and plays a role in lipid metabolism. Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1358-68.