Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTV75BJ)

DTT Name Carbohydrate antigen Lewis-Y (Lewis-Y)
Synonyms Lewis-Y carbohydrate antigen; Lewis-Y
Gene Name Lewis-Y
DTT Type
Clinical trial target
 [1]
UniProt ID
NOUNIPROTAC
TTD ID
T66514

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
CAR-T cells targeting Lewis-Y DMGI58S Solid tumour/cancer 2A00-2F9Z Phase 1 [1]
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1 Discontinued Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
IGN-311 DMBKZ4R Solid tumour/cancer 2A00-2F9Z Terminated [2]
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References

1 ClinicalTrials.gov (NCT03198052) HER2/Mesothelin/Lewis-Y/PSCA/MUC1/PD-L1/CD80/86-CAR-T Cells Immunotherapy Against Cancers
2 IGN-311. Igeneon. Curr Opin Investig Drugs. 2005 Dec;6(12):1272-9.