General Information of Drug Therapeutic Target (DTT) (ID: TTVFJLX)

DTT Name Peptide tyrosine tyrosine PYY (PYY)
Synonyms PYY-II
Gene Name PYY
DTT Type
Clinical trial target
[1]
BioChemical Class
NPY family
UniProt ID
PYY_HUMAN
TTD ID
T24127
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
IKPEAPREDASPEELNRYYASLRHYLNLVTRQRY
Function This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Reactome Pathway
G alpha (i) signalling events (R-HSA-418594 )
Peptide ligand-binding receptors (R-HSA-375276 )

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Peptide YY 3-36 DMNU48O Obesity 5B81 Phase 2 [1]
------------------------------------------------------------------------------------

References

1 Clinical pipeline report, company report or official report of Emisphere.