Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTY8LZG)
| DTT Name | Fos-related antigen 1 (FOSL1) | ||||
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| Synonyms | Fra-1; FRA1 | ||||
| Gene Name | FOSL1 | ||||
| DTT Type |
Literature-reported target
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[1] | |||
| BioChemical Class |
Basic leucine zipper bZIP
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| UniProt ID | |||||
| TTD ID | |||||
| 3D Structure | |||||
| Sequence |
MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG
PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL |
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| Function |
DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II proximal promoter sequence-specific DNA binding, cellular defense response, chemotaxis, positive regulation of cell population proliferation, positive regulation of DNA-templated transcription, initiation, pri-miRNA transcription by RNA polymerase II.
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| KEGG Pathway | |||||
| Reactome Pathway | |||||