General Information of Drug Therapeutic Target (DTT) (ID: TTYH1ZK)

DTT Name Beta-microseminoprotein (MSMB)
Synonyms Seminal plasma beta-inhibin; Prostate secretory protein of 94 amino acids; Prostate secreted seminal plasma protein; PSP94; PSP-94; PRSP; PN44; Immunoglobulin-binding factor; IGBF
Gene Name MSMB
DTT Type
Clinical trial target
[1]
UniProt ID
MSMB_HUMAN
TTD ID
T07374
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKGNKHPINSEWQTDNCETC
TCYETEISCCTLVSTPVGYDKDNCQRIFKKEDCKYIVVEKKDPKKTCSVSEWII
Function
A member of the immunoglobulin binding factor family. May have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. Inhibits growth of cancer cells in an experimental model of prostate cancer, though this property is cell line specific.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Clinical Trial Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tigapotide DMSVO92 Prostate cancer 2C82.0 Phase 1 [1]
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Molecular Expression Atlas (MEA) of This DTT

Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This DTT
Disease Name ICD 11 Studied Tissue p-value Fold-Change Z-score
Prostate cancer 2C82 Prostate 2.03E-10 -0.54 -1.21
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References

1 National Cancer Institute Drug Dictionary (drug id 600185).