General Information of Drug Therapeutic Target (DTT) (ID: TTYNM3X)

DTT Name Sugen kinase 110 (SBK3)
Synonyms Uncharacterized serine/threonine-protein kinase SBK3; SH3-binding domain kinase family member 3; SGK110
Gene Name SBK3
DTT Type
Literature-reported target
[1]
UniProt ID
SBK3_HUMAN
TTD ID
T89752
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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EC Number
EC 2.7.11.1
Sequence
MERRASETPEDGDPEEDTATALQRLVELTTSRVTPVRSLRDQYHLIRKLGSGSYGRVLLA
QPHQGGPAVALKLLRRDLVLRSTFLREFCVGRCVSAHPGLLQTLAGPLQTPRYFAFAQEY
APCGDLSGMLQERGLPELLVKRVVAQLAGALDFLHSRGLVHADVKPDNVLVFDPVCSRVA
LGDLGLTRPEGSPTPAPPVPLPTAPPELCLLLPPDTLPLRPAVDSWGLGVLLFCAATACF
PWDVALAPNPEFEAFAGWVTTKPQPPQPPPPWDQFAPPALALLQGLLDLDPETRSPPLAV
LDFLGDDWGLQGNREGPGVLGSAVSYEDREEGGSSLEEWTDEGDDSKSGGRTGTDGGAP
Function A serine/threonine protein kinase that does not have an activating compound and are either non-specific or their specificity has not been analyzed to date.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
PMID21967808CR-16 DMCOHKU Discovery agent N.A. Investigative [1]
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References

1 Improvement in oral bioavailability of 2,4-diaminopyrimidine c-Met inhibitors by incorporation of a 3-amidobenzazepin-2-one group. Bioorg Med Chem. 2011 Nov 1;19(21):6274-84.