General Information of Drug Therapeutic Target (DTT) (ID: TTYUB4M)

DTT Name G-protein coupled receptor 174 (GPR174)
Synonyms Probable G-protein coupled receptor 174
Gene Name GPR174
DTT Type
Literature-reported target
[1]
UniProt ID
GP174_HUMAN
TTD ID
T87661
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMIN
LAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFL
MYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLA
QSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFL
ICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFR
RRLSRQDLHDSIQLHAKSFVSNHTASTMTPELC
Function Putative receptor for purines coupled to G-proteins.

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This DTT
1 Investigative Drug(s) Targeting This DTT
Drug Name Drug ID Indication ICD 11 Highest Status REF
lysophosphatidylserine DMKG7J2 Discovery agent N.A. Investigative [1]
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References

1 TGFalpha shedding assay: an accurate and versatile method for detecting GPCR activation. Nat Methods. 2012 Oct;9(10):1021-9.