Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTYUK4F)

DTT Name	Myelin-associated/oligodendrocyte basic protein (MOBP)
Synonyms	Myelin-associated oligodendrocyte basic protein
Gene Name	MOBP
DTT Type	Literature-reported target	[1]
UniProt ID	MOBP_HUMAN
TTD ID	T70685
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MSQKPAKEGPRLSKNQKYSEHFSIHCCPPFTFLNSKKEIVDRKYSICKSGCFYQKKEEDW ICCACQKTRTSRRAKSPQRPKQQPAAPPAVVRAPAKPRSPPRSERQPRSPPRSERQPRSP PRSERQPRSPPRSERQPRPRPEVRPPPAKQRPPQKSKQQPRSSPLRGPGASRGGSPVKAS RFW
Function	May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
Reactome Pathway	Transcriptional Regulation by MECP2 (R-HSA-8986944 )

References

1	The central nervous system-specific myelin oligodendrocytic basic protein (MOBP) is encephalitogenic and a potential target antigen in multiple scl... J Neuroimmunol. 2000 Jan 24;102(2):189-98.