Details of the Drug Therapeutic Target (DTT)
General Information of Drug Therapeutic Target (DTT) (ID: TTZ1YIS)
DTT Name | HUMAN dCTP pyrophosphatase 1 | ||||
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Synonyms | XTP3-transactivated gene A protein ; RS21C6 ; Deoxycytidine-triphosphatase 1; dCTPase 1 | ||||
Gene Name | DCTPP1 | ||||
UniProt ID | |||||
TTD ID | |||||
3D Structure | |||||
EC Number |
EC 3.6.1.12
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Sequence |
MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLAL
VGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLS KMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST |
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Function | Human protein dCTP pyrophosphatase 1 interacts with SARS-CoV-2 Orf9b protein with high significance, which indicates DCTPP1 as a potential therapeutic target. | ||||
KEGG Pathway | |||||
Reactome Pathway | |||||