Details of the Drug Therapeutic Target (DTT)

General Information of Drug Therapeutic Target (DTT) (ID: TTZWSN5)

DTT Name	Amyloid precursor protein (APP)
Gene Name	APP
DTT Type	Literature-reported target	[1]
UniProt ID	NOUNIPROTAC
TTD ID	T55352

Molecular Interaction Atlas (MIA) of This DTT

Molecular Interaction Atlas (MIA)

Jump to Detail Molecular Interaction Atlas of This DTT

1 Clinical Trial Drug(s) Targeting This DTT

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
SHR-1707	DMCESPF	Alzheimer disease	8A20	Phase 1	[2]
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References

1	The Intracellular Domain of Amyloid Precursor Protein is a Potential Therapeutic Target in Alzheimer's Disease. Curr Drug Discov Technol. 2014;11(4):243-58.
2	ClinicalTrials.gov (NCT04973189) A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous Administration of SHR-1707 in Healthy Young Adult and Elderly Subjects. U.S.National Institutes of Health.