Details of the Drug Excipient
General Information of Drug Inactive Ingredient (DIG) (ID: E00461)
| DIG Name |
Hyaluronate sodium
|
||||
|---|---|---|---|---|---|
| Synonyms |
Healon; Hyaluronate Sodium; Hyaluronan; Kopuron; Hyalgan; Hyalurone sodium; Equron (Veterinary); Synacid (veterinary); Arthrease; Cystistat; Hyalart; Hyalein; Hyalovet; Hyladerm; Khionat; Monovisc; Nidelon; Orthovisc; Ostenil; Provisc; Sinovial; Supartz; Suvenyl; Hyasol; Hyladerm Khionat; Nrd101; Hyaluronsan HA-LQ; sodium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Bio Hyaluro 12; EUFLEXXA injection; EUFLEXXA; CCRIS 4127; Hyaluronate Sodium [USAN:JAN]; Sodium hyaluronate HMW; UNII-YSE9PPT4TH; SI-4402; SL-1010; Synacid; Equron; Chlamyhyaluronic acid sodium salt; SL 1010; Hyalauronic Acid 99%; YSE9PPT4TH; GTPL4954; Sodium Hyaluronate (Food Grade); EBD4181; Sodium Hyaluronate (Cosmetic Grade); AKOS015896610; Sodium Hyaluronate, Low Molecular Weight; Sodium Hyaluronate, High Molecular Weight; Q27078001; Hyaluronic acid sodium salt; Chlamyhyaluronic acid sodium salt; (3S,4R,5R,6R)-3-[(2S,3R,5S,6R)-3-acetamido-4-[(2S,3R,4S,6S)-6-carboxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]oxy-5-hydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-6-[(3R,4R,5S,6R)-3-acetamido-2,5-dih; sodium (2S,3S,4R,5R,6R)-3-{[(2S,3R,4R,5S,6R)-4-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-{[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid
|
||||
| DIG Function |
Humectant; Lubricant; Modified-release agent
|
||||
| Formula |
C28H44N2NaO23+
|
||||
| Canonical SMILES |
CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)NC(=O)C)O)O.[Na+]
|
||||
| InChI |
1S/C28H44N2O23.Na/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43;/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45);/q;+1/t7-,8-,9-,10-,11-,12-,13+,14+,15-,16-,17-,18-,19-,20+,21+,22+,25-,26+,27-,28-;/m1./s1
|
||||
| InChIKey |
YWIVKILSMZOHHF-QJZPQSOGSA-N
|
||||
| Physicochemical Properties | Molecular Weight | 799.6 | Topological Polar Surface Area | 400 | |
| XlogP | N.A. | Complexity | 1300 | ||
| Heavy Atom Count | 54 | Rotatable Bond Count | 12 | ||
| Hydrogen Bond Donor Count | 14 | Hydrogen Bond Acceptor Count | 23 | ||