Details of the Drug Formulaction

General Information of Drug Formulation (ID: F23581)

• Formulation Name: Trametinib Dimethyl Sulfoxide eq 2mg tablet
• Company: Novartis

Pharmaceutical Drug(s) in Formulation

Drug Name	Drug ID	Indication	ICD 11	Status
Trametinib	(DM2JGQ3)	Melanoma	2C30	Approved

Pharmaceutical Excipient(s) in Formulation

Excipient Name	Excipient ID	PubChem CID	Functional Classification
Carmellose sodium	(E00625)	Not Available	Disintegrant
Cellulose microcrystalline	(E00698)	Not Available	Adsorbent; Suspending agent; Diluent
Haematite red	(E00236)	14833	Colorant
Hydrophobic colloidal silica	(E00285)	24261	Anticaking agent; Emulsion stabilizing agent; Glidant; Suspending agent; Viscosity-controlling agent
Hypromellose	(E00634)	Not Available	Coating agent
Magnesium stearate	(E00208)	11177	lubricant
Mannitol	(E00103)	6251	Diluent; Flavoring agent; Lyophilization aid; Plasticizing agent; Tonicity agent
Polyethylene glycol 4000	(E00654)	Not Available	Coating agent; Diluent; Ointment base; Plasticizing agent; Solvent; Suppository base; lubricant
Polysorbate 80	(E00665)	Not Available	Dispersing agent; Emollient; Emulsifying agent; Plasticizing agent; Solubilizing agent; Surfactant; Suspending agent
Sodium lauryl sulfate	(E00464)	3423265	Emulsifying agent; Modified-release agent; Penetration agent; Solubilizing agent; Surfactant; lubricant
Titanium dioxide	(E00322)	26042	Coating agent; Colorant; Opacifying agent